Fibrin is a biological scaffold that forms in response to an injury anywhere in the body and platelets normally circulate within the blood and will bind to a scaffold of fibrin. When platelets bind to the scaffold, they become activated and release growth factors. These growth factors start the wound-healing process by creating new skin cells and blood vessels and collagen. Scientists have been able to figure out a way to take your blood, spin it in a centrifuge, isolate the contents, and create a platelet- and white blood cell–rich fibrin scaffold ready for use in plastic surgery. The platelet-rich fibrin has been used to fill in facial folds, scarring, wound healing, and better fat grafting